Code
|
Project title
|
Supervisor
|
Institution
|
| 22_01 |
Diversification of DNA-encoded libraries by photoredox catalysed sp3-coupling |
Mike Waring |
Newcastle |
| 22_02 |
Application of micellar catalysis to forbidden on-DNA reactions |
Mike Waring |
Newcastle |
| 22_03 |
Developing novel chemical probes to interrogate the allosteric mechanism of MTHFR and explore its therapeutic potential |
Celine Cano |
Newcastle |
| 22_04 |
Intracellular delivery of peptides using lipid-based nanoparticles |
Akane Kawamura |
Newcastle |
| 22_05 |
Neural networks for modelling protein conformational space Application to inhibitor design exploiting an enzymes mobile regulatory element |
Daniel Cole |
Newcastle |
| 22_06 |
Translating fragment maps to medical impact |
Jane Endicott |
Newcastle |
| 22_07 |
A novel drug discovery workflow combining DNA-encoded library, AI machine learning, and cryo-electron microscopy |
Wyatt Yue |
Newcastle |
| 22_08 |
MycoTACs Proteome targeting chimeras for Mycobacterium tuberculosis |
Jon Sellars |
Newcastle |
| 22_09 |
Linking epigenomics with cellular senescence to identify novel therapeutics for osteoarthritis |
Sarah Rice |
Newcastle |
| 22_10 |
Natural Products, Synthetic Biology and the Formulation of Novel Antimicrobials |
Paul Denny |
Durham |
| 22_11 |
New methods for scaled synthesis of nucleoside 5-triphosphates and their application in gene synthesis |
David Hodgson |
Durham |
| 22_12 |
Conjugation and encapsulation of photoactive metal complexes for medicinal applications |
Clare Mahon |
Durham |
| 22_13 |
Rapid Functional and Mechanical Characterisation of Neutrophil-Bacteria Interactions |
John Girkin |
Durham |
| 22_14 |
p53 function and metal levels in cancer cells |
Patricia Muller |
Durham |
| 22_15 |
Leveraging conformational control to access sp2
-rich 3D platforms for drug discovery |
Roly Armstrong |
Newcastle
|
| 22_16 |
Structure based developments of PROTAC drugs |
Ehmke Pohl |
Durham |
| 22_17 |
Proteome wide identification of clinically relevant carbon dioxide targets |
Martin Cann |
Durham |
